Human Immunodeficiency Virus Type 1 Nef Associates with Lipid Rafts To Downmodulate Cell Surface CD4 and Class I Major Histocompatibility Complex Expression and To Increase Viral Infectivity

Lipid rafts are membrane microdomains that are functionally distinct from other membrane regions. We have shown that 10% of human immunodeficiency virus type 1 (HIV-1) Nef expressed in SupT1 cells is present in lipid rafts and that this represents virtually all of the membrane-associated Nef. To det...

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Pubblicato in:	J Virol
Autori principali:	Alexander, Melissa, Bor, Yeou-cherng, Ravichandran, Kodimangalam S., Hammarskjöld, Marie-Louise, Rekosh, David
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2004
Soggetti:	Virus-Cell Interactions
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369412/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14747534/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.4.1685-1696.2004
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