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Human Immunodeficiency Virus Type 1 Nef Associates with Lipid Rafts To Downmodulate Cell Surface CD4 and Class I Major Histocompatibility Complex Expression and To Increase Viral Infectivity

Lipid rafts are membrane microdomains that are functionally distinct from other membrane regions. We have shown that 10% of human immunodeficiency virus type 1 (HIV-1) Nef expressed in SupT1 cells is present in lipid rafts and that this represents virtually all of the membrane-associated Nef. To det...

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Bibliografski detalji
Glavni autori: Alexander, Melissa, Bor, Yeou-cherng, Ravichandran, Kodimangalam S., Hammarskjöld, Marie-Louise, Rekosh, David
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC369412/
https://ncbi.nlm.nih.gov/pubmed/14747534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.4.1685-1696.2004
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