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Germinal Center B-Cells Resist Transformation by Kras Independently of Tumor Suppressor Arf

Activating mutations in Ras (N- and K-) are the most common point mutations found in patients with multiple myeloma (MM) and are associated with poor clinical outcome. We sought to directly examine the role of Ras activation in MM pathogenesis and used two different tissue-specific Cre recombinase m...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mullins, Chelsea D., Su, Mack Y., Hucthagowder, Vishwanathan, Chu, Liang, Lu, Lan, Kulkarni, Shashikant, Novack, Deborah, Vij, Ravi, Tomasson, Michael H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3692489/
https://ncbi.nlm.nih.gov/pubmed/23825691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067941
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