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Isotope Effects and Mechanism of the Asymmetric BOROX Brønsted Acid Catalyzed Aziridination Reaction

The mechanism of the chiral VANOL-BOROX Brønsted acid catalyzed aziridination reaction of imines and ethyldiazoacetate has been studied using a combination of experimental kinetic isotope effects and theoretical calculations. A stepwise mechanism where reversible formation of a diazonium ion interme...

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Détails bibliographiques
Auteurs principaux: Vetticatt, Mathew J., Desai, Aman A., Wulff, William D.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3692281/
https://ncbi.nlm.nih.gov/pubmed/23687986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo302783d
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