Protection against Mucosal Simian Immunodeficiency Virus SIV(mac251) Challenge by Using Replicating Adenovirus-SIV Multigene Vaccine Priming and Subunit Boosting

Whereas several recent AIDS vaccine strategies have protected rhesus macaques against a pathogenic simian/human immunodeficiency virus (SHIV)(89.6P) challenge, similar approaches have provided only modest, transient reductions in viral burden after challenge with virulent, pathogenic SIV, which is m...

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Detalhes bibliográficos
Main Authors: Patterson, L. Jean, Malkevitch, Nina, Venzon, David, Pinczewski, Joel, Gómez-Román, Victor Raúl, Wang, Liqun, Kalyanaraman, V. S., Markham, Phillip D., Robey, Frank A., Robert-Guroff, Marjorie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC369221/
https://ncbi.nlm.nih.gov/pubmed/14963117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.5.2212-2221.2004
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