High level of susceptibility to human TRIM5α conferred by HIV-2 capsid sequences

BACKGROUND: HIV-2, which was transmitted to humans from a distant primate species (sooty mangabey), differs remarkably from HIV-1 in its infectivity, transmissibility and pathogenicity. We have tested the possibility that a greater susceptibility of HIV-2 capsid (CA) to the human restriction factor...

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Bibliografiska uppgifter
Huvudupphovsmän: Takeuchi, Junko S, Perche, Benjamin, Migraine, Julie, Mercier-Delarue, Séverine, Ponscarme, Diane, Simon, François, Clavel, François, Labrosse, Béatrice
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2013
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691696/
https://ncbi.nlm.nih.gov/pubmed/23647667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-50
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