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Labeling and Identification of Direct Kinase Substrates

Identifying kinase substrates is an important step in mapping signal transduction pathways, but remains a difficult and time-consuming process. Analog-sensitive kinases (AS-kinases) have been used to selectively tag and identify direct kinase substrates in lysates from whole cells. In this approach...

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Detalhes bibliográficos
Main Authors: Carlson, Scott M., White, Forest M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690949/
https://ncbi.nlm.nih.gov/pubmed/22669844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2002568
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