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High-resolution structures of the IgM Fc domains reveal principles of its hexamer formation
IgM is the first antibody produced during the humoral immune response. Despite its fundamental role in the immune system, IgM is structurally only poorly described. In this work we used X-ray crystallography and NMR spectroscopy to determine the atomic structures of the constant IgM Fc domains (Cµ2,...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3690842/ https://ncbi.nlm.nih.gov/pubmed/23733956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300547110 |
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