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The impact of acetylation and deacetylation on the p53 pathway

The p53 tumor suppressor is a sequence-specific transcription factor that undergoes an abundance of post-translational modifications for its regulation and activation. Acetylation of p53 is an important reversible enzymatic process that occurs in response to DNA damage and genotoxic stress and is in...

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Detalles Bibliográficos
Main Authors: Brooks, Christopher L., Gu, Wei
Formato: Artigo
Idioma:Inglês
Publicado: Higher Education Press 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690542/
https://ncbi.nlm.nih.gov/pubmed/21748595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1063-9
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