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FBXO11 Promotes the Neddylation of p53 and Inhibits Its Transcriptional Activity()
The p53 tumor suppressor is regulated by post-translational modification, including ubiquitination, phosphorylation and acetylation. It has previously been shown that the ubiquitin ligase Mdm2 also promotes the conjugation of Nedd8, a ubiquitin-like protein, to p53, inhibiting its transcriptional ac...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3690493/ https://ncbi.nlm.nih.gov/pubmed/17098746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M609001200 |
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