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Regulation of nucleolar signalling to p53 through NEDDylation of L11

Several studies have shown that ribosomal proteins (RPs) are important mediators of p53 activation in response to nucleolar disruption; however, the pathways that control this signalling function of RPs are currently unknown. We have recently shown that RPs are targets for the ubiquitin-like molecul...

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Detalhes bibliográficos
Main Authors: Sundqvist, Anders, Liu, Geng, Mirsaliotis, Antonis, Xirodimas, Dimitris P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759733/
https://ncbi.nlm.nih.gov/pubmed/19713960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.178
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