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FBXO11 Promotes the Neddylation of p53 and Inhibits Its Transcriptional Activity()

The p53 tumor suppressor is regulated by post-translational modification, including ubiquitination, phosphorylation and acetylation. It has previously been shown that the ubiquitin ligase Mdm2 also promotes the conjugation of Nedd8, a ubiquitin-like protein, to p53, inhibiting its transcriptional ac...

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Hlavní autoři: Abida, Wassim M., Nikolaev, Anatoly, Zhao, Wenhui, Zhang, Wenzhu, Gu, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690493/
https://ncbi.nlm.nih.gov/pubmed/17098746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M609001200
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