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The C-terminal Domain of A1/Bfl-1 Regulates its Anti-inflammatory Function in Human Endothelial Cells

A1/Bfl-1 is a NF-κB dependent, anti-apoptotic Bcl-2 family member that contains four Bcl-2 homology domains (BH) and an amphipathic C-terminal domain, and is expressed in endothelial cells (EC). Based on NF-κB reporter assays in bovine aortic EC, we have previously demonstrated that A1, like Bcl-2 a...

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Detalhes bibliográficos
Main Authors: Guedes, Renata P., Rocha, Eduardo, Mahiou, Jerome, Moll, Herwig P., Arvelo, Maria B., Taube, Janis M., Peterson, Clayton R., Kaczmarek, Elzbieta, Longo, Christopher R., da Silva, Cleide G., Ferran, Christiane
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690303/
https://ncbi.nlm.nih.gov/pubmed/23499873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2013.03.001
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