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Mechanism of purinergic activation of endothelial nitric oxide synthase in endothelial cells

BACKGROUND: Decreased endothelial nitric oxide synthase (eNOS) activity and nitric oxide (NO) production are critical contributors to endothelial dysfunction and vascular complications observed in many diseases, including diabetes mellitus. Extracellular nucleotides activate eNOS and increase NO gen...

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Detalhes bibliográficos
Main Authors: da Silva, Cleide Gonçalves, Specht, Anke, Wegiel, Barbara, Ferran, Christiane, Kaczmarek, Elzbieta
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702845/
https://ncbi.nlm.nih.gov/pubmed/19188511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.764571
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