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Mechanism of purinergic activation of endothelial nitric oxide synthase in endothelial cells

BACKGROUND: Decreased endothelial nitric oxide synthase (eNOS) activity and nitric oxide (NO) production are critical contributors to endothelial dysfunction and vascular complications observed in many diseases, including diabetes mellitus. Extracellular nucleotides activate eNOS and increase NO gen...

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Main Authors: da Silva, Cleide Gonçalves, Specht, Anke, Wegiel, Barbara, Ferran, Christiane, Kaczmarek, Elzbieta
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702845/
https://ncbi.nlm.nih.gov/pubmed/19188511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.764571
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