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A20 deficiency causes spontaneous neuroinflammation in mice

BACKGROUND: A20 (TNFAIP3) is a pleiotropic NFκB-dependent gene that terminates NFκB activation in response to inflammatory stimuli. The potent anti-inflammatory properties of A20 are well characterized in several organs. However, little is known about its role in the brain. In this study, we investi...

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Detalhes bibliográficos
Main Authors: Guedes, Renata Padilha, Csizmadia, Eva, Moll, Herwig P, Ma, Averil, Ferran, Christiane, da Silva, Cleide Gonçalves
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128606/
https://ncbi.nlm.nih.gov/pubmed/25026958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-122
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