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Early stage development of the glycine-1 re-uptake inhibitor SCH 900435: central nervous system effects compared with placebo in healthy men

AIMS: To report the first three studies with SCH 900435, a selective glycine-1 re-uptake inhibitor in development for treating schizophrenia, using systematic evaluations of pharmacodynamics to understand the observed effects. METHODS: Three double-blind, placebo-controlled studies (single, visual e...

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Detalhes bibliográficos
Main Authors: Liem-Moolenaar, Marieke, Peeters, Pierre, Kamerling, Ingrid M C, Hogg, Chris, Holder, Graham, Kleijn, Huub Jan, Spaans, Edwin, Udo De Haes, Joanna, de Kam, Marieke L, Franson, Kari L, Cohen, Adam F, van Gerven, Joop M A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690104/
https://ncbi.nlm.nih.gov/pubmed/23116363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12015
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