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Vps9 Family Protein Muk1 Is the Second Rab5 Guanosine Nucleotide Exchange Factor in Budding Yeast

VPS9 domains can act as guanosine nucleotide exchange factors (GEFs) against small G proteins of the Rab5 family. Saccharomyces cerevisiae vps9Δ mutants have trafficking defects considerably less severe than multiple deletions of the three cognate Rab5 paralogs (Vps21, Ypt52, and Ypt53). Here, we sh...

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Autors principals: Paulsel, Andrew L., Merz, Alexey J., Nickerson, Daniel P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689959/
https://ncbi.nlm.nih.gov/pubmed/23612966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.457069
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