Llwytho...
Structural basis for Rab GTPase activation by VPS9 domain exchange factors
RABEX-5 and other exchange factors with VPS9 domains regulate endocytic trafficking through activation of the Rab family GTPases RAB5, RAB21 and RAB22. Here we report the crystal structure of the RABEX-5 catalytic core in complex with nucleotide-free RAB21, a key intermediate in the exchange reactio...
Wedi'i Gadw mewn:
| Prif Awduron: | , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2007
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2254184/ https://ncbi.nlm.nih.gov/pubmed/17450153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1232 |
| Tagiau: |
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