Lacritin Rescues Stressed Epithelia via Rapid Forkhead Box O3 (FOXO3)-associated Autophagy That Restores Metabolism

Homeostasis is essential for cell survival. However, homeostatic regulation of surface epithelia is poorly understood. The eye surface, lacking the cornified barrier of skin, provides an excellent model. Tears cover the surface of the eye and are deficient in dry eye, the most common eye disease aff...

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Detalhes bibliográficos
Main Authors: Wang, Ningning, Zimmerman, Keith, Raab, Ronald W., McKown, Robert L., Hutnik, Cindy M. L., Talla, Venu, Tyler, Milton F., Lee, Jae K., Laurie, Gordon W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689958/
https://ncbi.nlm.nih.gov/pubmed/23640897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.436584
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