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Conserved Regional 3′ Grouping of Rare Codons in the Coding Sequence of Ocular Prosecretory Mitogen Lacritin

PURPOSE. Lacritin is a prosecretory mitogen in tears and, although a tear protein, it promotes basal tearing and lacrimal gland secretion. Since scale up is relevant to its potential use in the treatment of dry eye, we explored various mutagenic strategies to alter the stability, solubility, and tra...

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Detalhes bibliográficos
Main Authors: McKown, Robert L., Raab, Ronald W., Kachelries, Patricia, Caldwell, Sara, Laurie, Gordon W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604909/
https://ncbi.nlm.nih.gov/pubmed/23422824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10740
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