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Conserved Regional 3′ Grouping of Rare Codons in the Coding Sequence of Ocular Prosecretory Mitogen Lacritin

PURPOSE. Lacritin is a prosecretory mitogen in tears and, although a tear protein, it promotes basal tearing and lacrimal gland secretion. Since scale up is relevant to its potential use in the treatment of dry eye, we explored various mutagenic strategies to alter the stability, solubility, and tra...

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Autors principals: McKown, Robert L., Raab, Ronald W., Kachelries, Patricia, Caldwell, Sara, Laurie, Gordon W.
Format: Artigo
Idioma:Inglês
Publicat: The Association for Research in Vision and Ophthalmology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604909/
https://ncbi.nlm.nih.gov/pubmed/23422824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10740
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