Regulation of Rad17 Protein Turnover Unveils an Impact of Rad17-APC Cascade in Breast Carcinogenesis and Treatment

Aberrant regulation of DNA damage checkpoint function leads to genome instability that in turn can predispose cellular tissues to become cancerous. Previous works from us and others demonstrated the role of Rad17 in either activation or termination of DNA damage checkpoint function. In the current s...

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Autors principals: Zhou, Zhuan, Jing, Chao, Zhang, Liyong, Takeo, Fujita, Kim, Hyun, Huang, Yi, Liu, Zhihua, Wan, Yong
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689957/
https://ncbi.nlm.nih.gov/pubmed/23637229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.456962
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