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Novel Insight into KLF4 Proteolytic Regulation in Estrogen Receptor Signaling and Breast Carcinogenesis

Krüppel-like factor 4 (KLF4), a zinc finger-containing transcriptional factor, is a pivotal regulator of cellular fate. KLF4 has attracted considerable attention for its opposing effect in carcinogenesis as tumor suppressor (e.g. colorectal cancer) or oncoprotein (e.g. breast cancer), depending on t...

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Detalhes bibliográficos
Main Authors: Hu, Dong, Zhou, Zhuan, Davidson, Nancy E., Huang, Yi, Wan, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340146/
https://ncbi.nlm.nih.gov/pubmed/22389506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.343566
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