p39, the Primary Activator for Cyclin-dependent Kinase 5 (Cdk5) in Oligodendroglia, Is Essential for Oligodendroglia Differentiation and Myelin Repair

Cyclin-dependent kinase 5 (Cdk5) plays key roles in normal brain development and function. Dysregulation of Cdk5 may cause neurodegeneration and cognitive impairment. Besides the well demonstrated role of Cdk5 in neurons, emerging evidence suggests the functional requirement of Cdk5 in oligodendrogl...

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Autores principales: Bankston, Andrew N., Li, Wenqi, Zhang, Hui, Ku, Li, Liu, Guanglu, Papa, Filomena, Zhao, Lixia, Bibb, James A., Cambi, Franca, Tiwari-Woodruff, Seema K., Feng, Yue
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Neurobiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689949/
https://ncbi.nlm.nih.gov/pubmed/23645679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.453688
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