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PIKE is essential for oligodendroglia development and CNS myelination

Oligodendrocyte (OL) differentiation and myelin development are complex events regulated by numerous signal transduction factors. Here, we report that phosphoinositide-3 kinase enhancer L (PIKE-L) is required for OL development and myelination. PIKE-L expression is up-regulated when oligodendrocyte...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chan, Chi Bun, Liu, Xia, Zhao, Lixia, Liu, Guanglu, Lee, Chi Wai, Feng, Yue, Ye, Keiqang
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918755/
https://ncbi.nlm.nih.gov/pubmed/24449917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318185111
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