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PIKE is essential for oligodendroglia development and CNS myelination
Oligodendrocyte (OL) differentiation and myelin development are complex events regulated by numerous signal transduction factors. Here, we report that phosphoinositide-3 kinase enhancer L (PIKE-L) is required for OL development and myelination. PIKE-L expression is up-regulated when oligodendrocyte...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3918755/ https://ncbi.nlm.nih.gov/pubmed/24449917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318185111 |
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