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Analysis of TP53 mutation spectra reveals the fingerprint of the potent environmental carcinogen, aristolochic acid
Genetic alterations in cancer tissues may reflect the mutational fingerprint of environmental carcinogens. Here we review the evidence that support the role of aristolochic acid (AA) in inducing a mutational fingerprint in the tumor suppressor gene TP53 in urothelial carcinomas of the upper urinary...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3689860/ https://ncbi.nlm.nih.gov/pubmed/23422071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrrev.2013.02.003 |
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