2-phenylethynesulfonamide Prevents Induction of Pro-inflammatory Factors and Attenuates LPS-induced Liver Injury by Targeting NHE1-Hsp70 Complex in Mice

The endotoxin-mediated production of pro-inflammatory cytokines plays an important role in the pathogenesis of liver disorders. Heat shock protein (Hsp70) overexpression has established functions in lipopolysaccharide (LPS)-mediated inflammatory response. However, little is known about the role of H...

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Bibliographic Details
Main Authors: Huang, Chao, Wang, Jia, Chen, Zhuo, Wang, Yuzhe, Zhang, Wei
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689707/
https://ncbi.nlm.nih.gov/pubmed/23805318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067582
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