Functional Integration of the Conserved Domains of Shoc2 Scaffold

Shoc2 is a positive regulator of signaling to extracellular signal-regulated protein kinases 1 and 2 (ERK1/2). Shoc2 is also proposed to interact with RAS and Raf-1 in order to accelerate ERK1/2 activity. To understand the mechanisms by which Shoc2 regulates ERK1/2 activation by the epidermal growth...

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Bibliografiske detaljer
Main Authors: Jeoung, Myoungkun, Abdelmoti, Lina, Jang, Eun Ryoung, Vander Kooi, Craig W., Galperin, Emilia
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689688/
https://ncbi.nlm.nih.gov/pubmed/23805200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066067
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