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HUWE1 Is a Molecular Link Controlling RAF-1 Activity Supported by the Shoc2 Scaffold
Scaffold proteins play a critical role in controlling the activity of the extracellular signal-regulated kinase 1/2 (ERK1/2) pathway. Shoc2 is a leucine-rich repeat scaffold protein that acts as a positive modulator of ERK1/2 signaling. However, the precise mechanism by which Shoc2 modulates the act...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4187736/ https://ncbi.nlm.nih.gov/pubmed/25022756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00811-14 |
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