Llwytho...

Activation of Specific Apoptotic Caspases with an Engineered Small Molecule-Activated Protease

Apoptosis is a conserved cellular pathway that results in the activation of cysteine-aspartyl proteases, or caspases. To dissect the non-redundant roles of the executioner caspases-3, -6 and -7 in orchestrating apoptosis, we have developed an orthogonal protease to selectively activate each isoform...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gray, Daniel C., Mahrus, Sami, Wells, James A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689538/
https://ncbi.nlm.nih.gov/pubmed/20723762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.07.014
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