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BRCA1 in the DNA damage response and at telomeres
Mutations of the breast and ovarian cancer susceptibility gene 1 (BRCA1) account for about 40–45% of hereditary breast cancer cases. Moreover, a significant fraction of sporadic (non-hereditary) breast and ovarian cancers exhibit reduced or absent expression of the BRCA1 protein, suggesting an addit...
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| Formato: | Artigo |
| Idioma: | Inglês |
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Frontiers Media S.A.
2013
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3689208/ https://ncbi.nlm.nih.gov/pubmed/23802008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00085 |
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