HSV activates Akt to trigger calcium release and promote viral entry: novel candidate target for treatment and suppression

HSV triggers intracellular calcium release to promote viral entry. We hypothesized that Akt signaling induces the calcium responses and contributes to HSV entry. Exposure of human cervical and primary genital tract epithelial, neuronal, or keratinocyte cells to HSV serotype 2 resulted in rapid phosp...

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Detalhes bibliográficos
Main Authors: Cheshenko, Natalia, Trepanier, Janie B., Stefanidou, Martha, Buckley, Niall, Gonzalez, Pablo, Jacobs, William, Herold, Betsy C.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2013
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688744/
https://ncbi.nlm.nih.gov/pubmed/23507869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-220285
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