HSV activates Akt to trigger calcium release and promote viral entry: novel candidate target for treatment and suppression

HSV triggers intracellular calcium release to promote viral entry. We hypothesized that Akt signaling induces the calcium responses and contributes to HSV entry. Exposure of human cervical and primary genital tract epithelial, neuronal, or keratinocyte cells to HSV serotype 2 resulted in rapid phosp...

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Bibliografiske detaljer
Main Authors: Cheshenko, Natalia, Trepanier, Janie B., Stefanidou, Martha, Buckley, Niall, Gonzalez, Pablo, Jacobs, William, Herold, Betsy C.
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2013
Fag:
Research Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688744/
https://ncbi.nlm.nih.gov/pubmed/23507869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-220285
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