Herpes Simplex Virus 2 (HSV-2) Prevents Dendritic Cell Maturation, Induces Apoptosis, and Triggers Release of Proinflammatory Cytokines: Potential Links to HSV-HIV Synergy

Herpes simplex virus 2 (HSV-2) may cause frequent recurrences, highlighting its ability to evade host defense. This study tested the hypothesis that HSV-2 interferes with dendritic cell (DC) function as an escape mechanism, which may contribute to enhanced HIV replication in coinfected populations....

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Detalhes bibliográficos
Main Authors: Stefanidou, Martha, Ramos, Irene, Mas Casullo, Veronica, Trépanier, Janie B., Rosenbaum, Sara, Fernandez-Sesma, Ana, Herold, Betsy C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554174/
https://ncbi.nlm.nih.gov/pubmed/23152529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01302-12
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