SCF E3 ligase F-box protein complex SCF(FBXL19) regulates cell migration by mediating Rac1 ubiquitination and degradation

Rac1, a member of the Rho family of GTPases, regulates diverse cellular functions, including cytoskeleton reorganization and cell migration. F-box proteins are major subunits within the Skp1-Cul1-F-box (SCF) E3 ubiquitin ligases that recognize specific substrates for ubiquitination. The role of F-bo...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhao, Jing, Mialki, Rachel K., Wei, Jianxin, Coon, Tiffany A., Zou, Chunbin, Chen, Bill B., Mallampalli, Rama K., Zhao, Yutong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Federation of American Societies for Experimental Biology 2013
Konular:
Research Communications
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688740/
https://ncbi.nlm.nih.gov/pubmed/23512198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-223099
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