A Point Mutation within Conserved Region VI of Herpes Simplex Virus Type 1 DNA Polymerase Confers Altered Drug Sensitivity and Enhances Replication Fidelity

Herpes simplex virus type 1 (HSV-1) DNA polymerase contains several conserved regions within the polymerase domain. The conserved regions I, II, III, V, and VII have been shown to have functional roles in the interaction with deoxynucleoside triphosphates (dNTPs) and DNA. However, the role of conser...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Hwang, Ying T., Zuccola, Harmon J., Lu, Qiaosheng, Hwang, Charles B. C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Replication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC368862/
https://ncbi.nlm.nih.gov/pubmed/14694096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.2.650-657.2004
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares