Imparting Temperature Sensitivity and Attenuation in Ferrets to A/Puerto Rico/8/34 Influenza Virus by Transferring the Genetic Signature for Temperature Sensitivity from Cold-Adapted A/Ann Arbor/6/60

The four temperature-sensitive (ts) loci identified in the PB1 and PB2 gene segments of cold-adapted A/Ann Arbor/6/60 influenza virus, the master donor virus for influenza A virus (MDV-A) FluMist vaccines, were introduced into a divergent A/Puerto Rico/8/34 influenza virus strain. Recombinant A/Puer...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	J Virol
Autori principali:	Jin, Hong, Zhou, Helen, Lu, Bin, Kemble, George
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2004
Soggetti:	Vaccines and Antiviral Agents
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC368857/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14694130/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.2.995-998.2004
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!