Location of the CD8 T Cell Epitope within the Antigenic Precursor Determines Immunogenicity and Protection against the Toxoplasma gondii Parasite

CD8 T cells protect the host from disease caused by intracellular pathogens, such as the Toxoplasma gondii (T. gondii) protozoan parasite. Despite the complexity of the T. gondii proteome, CD8 T cell responses are restricted to only a small number of peptide epitopes derived from a limited set of an...

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Main Authors: Feliu, Virginie, Vasseur, Virginie, Grover, Harshita S., Chu, H. Hamlet, Brown, Mark J., Wang, Jeremy, Boyle, Jon P., Robey, Ellen A., Shastri, Nilabh, Blanchard, Nicolas
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688528/
https://ncbi.nlm.nih.gov/pubmed/23818852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003449
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