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Characterization of the Inhibition of Hepatitis C Virus RNA Replication by Nonnucleosides

The RNA-dependent RNA polymerase of hepatitis C virus (HCV) is necessary for the replication of viral RNA and thus represents an attractive target for drug development. Several structural classes of nonnucleoside inhibitors (NNIs) of HCV RNA polymerase have been described, including a promising seri...

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Autors principals: Tomei, Licia, Altamura, Sergio, Bartholomew, Linda, Bisbocci, Monica, Bailey, Carolyn, Bosserman, Michele, Cellucci, Antonella, Forte, Eleonora, Incitti, Ilario, Orsatti, Laura, Koch, Uwe, De Francesco, Raffaele, Olsen, David B., Carroll, Steven S., Migliaccio, Giovanni
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC368780/
https://ncbi.nlm.nih.gov/pubmed/14694125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.2.938-946.2004
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