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Characterization of the Inhibition of Hepatitis C Virus RNA Replication by Nonnucleosides

The RNA-dependent RNA polymerase of hepatitis C virus (HCV) is necessary for the replication of viral RNA and thus represents an attractive target for drug development. Several structural classes of nonnucleoside inhibitors (NNIs) of HCV RNA polymerase have been described, including a promising seri...

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Bibliografiske detaljer
Main Authors: Tomei, Licia, Altamura, Sergio, Bartholomew, Linda, Bisbocci, Monica, Bailey, Carolyn, Bosserman, Michele, Cellucci, Antonella, Forte, Eleonora, Incitti, Ilario, Orsatti, Laura, Koch, Uwe, De Francesco, Raffaele, Olsen, David B., Carroll, Steven S., Migliaccio, Giovanni
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC368780/
https://ncbi.nlm.nih.gov/pubmed/14694125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.2.938-946.2004
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