Persistent Recognition of Autologous Virus by High-Avidity CD8 T Cells in Chronic, Progressive Human Immunodeficiency Virus Type 1 Infection

CD8 T-cell responses are thought to be crucial for control of viremia in human immunodeficiency virus (HIV) infection but ultimately fail to control viremia in most infected persons. Studies in acute infection have demonstrated strong CD8-mediated selection pressure and evolution of mutations confer...

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Autori principali: Draenert, R., Verrill, C. L., Tang, Y., Allen, T. M., Wurcel, A. G., Boczanowski, M., Lechner, A., Kim, A. Y., Suscovich, T., Brown, N. V., Addo, M. M., Walker, B. D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC368768/
https://ncbi.nlm.nih.gov/pubmed/14694094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.2.630-641.2004
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