Limited Sequence Evolution within Persistently Targeted CD8 Epitopes in Chronic Human Immunodeficiency Virus Type 1 Infection

Studies in acute human immunodeficiency virus type 1 (HIV-1) infection indicate viral evolution under CD8 T-cell immune selection pressure, but the effects of ongoing immune pressure on epitope evolution during chronic infection are not well described. In this study, we performed a detailed longitud...

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Detalhes bibliográficos
Main Authors: Koibuchi, Tomohiko, Allen, Todd M., Lichterfeld, Mathias, Mui, Stanley K., O'Sullivan, Kristin M., Trocha, Alicja, Kalams, Spyros A., Johnson, R. Paul, Walker, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1143727/
https://ncbi.nlm.nih.gov/pubmed/15956562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.13.8171-8181.2005
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