The FAAH inhibitor URB597 efficiently reduces tyrosine hydroxylase expression through CB(1)- and FAAH-independent mechanisms

BACKGROUND: Anandamide and 2-arachidonoylglycerol are neuromodulatory lipids interacting with cannabinoid receptors, whose availability is regulated by the balance between ‘on demand’ generation and enzymatic degradation [by fatty acid amide hydrolase (FAAH)/monoacylglycerol lipase]. Given the repor...

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Hlavní autoři: Bosier, Barbara, Muccioli, Giulio G, Lambert, Didier M
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2013
Témata:
Themed Section: Cannabinoids 2012, Part Two
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687660/
https://ncbi.nlm.nih.gov/pubmed/22970888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02208.x
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