A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol with potential anti-obesity effects

BACKGROUND AND PURPOSE: The development of potent and selective inhibitors of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol (2-AG) via DAG lipases (DAGL) α and β is just starting to be considered as a novel and promising source of pharmaceuticals for the treatment of disorders that...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Bisogno, Tiziana, Mahadevan, Anu, Coccurello, Roberto, Chang, Jae Won, Allarà, Marco, Chen, Yugang, Giacovazzo, Giacomo, Lichtman, Aron, Cravatt, Benjamin, Moles, Anna, Di Marzo, Vincenzo
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2013
Témata:
Themed Section: Cannabinoids 2012, Part Two
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687659/
https://ncbi.nlm.nih.gov/pubmed/23072382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12013
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky