Human Immunodeficiency Virus Type 1 Tat Regulates Endothelial Cell Actin Cytoskeletal Dynamics through PAK1 Activation and Oxidant Production

Human immunodeficiency virus type 1 Tat exerts prominent angiogenic effects which may lead to a variety of vasculopathic conditions in AIDS patients. Because endothelial cells undergo prominent cytoskeletal rearrangement during angiogenesis, we investigated the specific effects of Tat on the endothe...

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Detalhes bibliográficos
Main Authors: Wu, Ru Feng, Gu, Ying, Xu, You Cheng, Mitola, Stefania, Bussolino, Federico, Terada, Lance S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC368750/
https://ncbi.nlm.nih.gov/pubmed/14694110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.2.779-789.2004
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