Identification of Specific Molecular Structures of Human Immunodeficiency Virus Type 1 Tat Relevant for Its Biological Effects on Vascular Endothelial Cells

Human immunodeficiency virus type 1 (HIV-1) Tat transactivates viral genes and is released by infected cells, acting as a soluble mediator. In endothelial cells (EC), it activates a proangiogenic program by activating vascular endothelial growth factor receptor type 2 (VEGFR-2) and integrins. A stru...

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Detalhes bibliográficos
Main Authors: Mitola, Stefania, Soldi, Raffaella, Zanon, Ilaria, Barra, Luca, Gutierrez, Maria Ines, Berkhout, Ben, Giacca, Mauro, Bussolino, Federico
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC111545/
https://ncbi.nlm.nih.gov/pubmed/10590123
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