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Mechanisms of resistance to reversible inhibitors of EGFR tyrosine kinase in non-small cell lung cancer

Abnormalities of epidermal growth factor receptor (EGFR) in non-small-cell lung cancer (NSCLC) patients consist of EGFR overexpression and EGFR (HER1) gene mutations. Structural dysfunction of the tyrosine kinase domain of EGFR is associated with the clinical response to tyrosine kinase inhibitors (...

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Bibliografische gegevens
Hoofdauteurs: Krawczyk, Paweł, Mlak, Radosław, Powrózek, Tomasz, Nicoś, Marcin, Kowalski, Dariusz M., Wojas-Krawczyk, Kamila, Milanowski, Janusz
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Termedia Publishing House 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687444/
https://ncbi.nlm.nih.gov/pubmed/23788917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/wo.2012.31768
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