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Induction of metallothionein-I mRNA in cultured cells by heavy metals and iodoacetate: evidence for gratuitous inducers.

A mouse hepatocyte cell line selected for growth in 80 microM CdSO4 (Cdr80 cells) was used to test the role of metallothioneins in heavy metal detoxification. The cadmium-resistant (Cdr80) cells have double minute chromosomes carrying amplified copies of the metallothionein-I gene and accumulate ca....

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Bibliografische gegevens
Hoofdauteurs: Durnam, D M, Palmiter, R D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1984
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC368726/
https://ncbi.nlm.nih.gov/pubmed/6717431
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