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Induction of metallothionein-I mRNA in cultured cells by heavy metals and iodoacetate: evidence for gratuitous inducers.

A mouse hepatocyte cell line selected for growth in 80 microM CdSO4 (Cdr80 cells) was used to test the role of metallothioneins in heavy metal detoxification. The cadmium-resistant (Cdr80) cells have double minute chromosomes carrying amplified copies of the metallothionein-I gene and accumulate ca....

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Bibliografische gegevens
Gepubliceerd in:Mol Cell Biol
Hoofdauteurs: Durnam, D M, Palmiter, R D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 1984
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC368726/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6717431/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.4.3.484
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