טוען...
Intrinsic Disorder in PTEN and its Interactome Confers Structural Plasticity and Functional Versatility
IDPs, while structurally poor, are functionally rich by virtue of their flexibility and modularity. However, how mutations in IDPs elicit diseases, remain elusive. Herein, we have identified tumor suppressor PTEN as an intrinsically disordered protein (IDP) and elucidated the molecular principles by...
שמור ב:
| Main Authors: | , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3687229/ https://ncbi.nlm.nih.gov/pubmed/23783762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02035 |
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