Comparative genomics, molecular evolution and computational modeling of ALDH1B1 and ALDH2

Vertebrate ALDH2 genes encode mitochondrial enzymes capable of metabolizing acetaldehyde and other biological aldehydes in the body. Mammalian ALDH1B1, another mitochondrial enzyme sharing 72% identity with ALDH2, is also capable of metabolizing acetaldehyde but has a tissue distribution and pattern...

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Hauptverfasser: Jackson, Brian C., Holmes, Roger S., Backos, Donald S., Reigan, Philip, Thompson, David C., Vasiliou, Vasilis
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687035/
https://ncbi.nlm.nih.gov/pubmed/23247008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2012.11.022
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